Search on: RECEPTOR, TRKA 
Descriptors Found: 1
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Descriptor English:   Receptor, trkA 
Descriptor Spanish:   Receptor trkA 
Descriptor Portuguese:   Receptor trkA 
Synonyms English:   Neurotrophic Tyrosine Kinase Receptor Type 1
Proto-Oncogene Products c-trk
c-trk Protein
gp140 c-trk
p140-trkA
trk1 Transforming Tryrosine Kinase
Proto Oncogene Products c trk
Proto Oncogene Protein trk
Proto-Oncogene Protein, trk
Receptor, NTRK1
c trk Protein
c-trk, Proto-Oncogene Products
c-trk, gp140
gp140 c trk
p140 trkA
trk Proto Oncogene Protein
trk, Proto-Oncogene Protein
gp140(c-TRK)
trk Proto-Oncogene Protein
trkA Receptor
NTRK1 Receptor
Proto-Oncogene Protein trk
Receptor, Neurotrophic Tyrosine Kinase Type 1  
Tree Number:   D08.811.913.696.620.682.725.400.660
D12.776.543.750.630.496
D12.776.543.750.750.400.550.550
Definition English:   A protein-tyrosine kinase receptor that is specific for NERVE GROWTH FACTOR; NEUROTROPHIN 3; neurotrophin 4, neurotrophin 5. It plays a crucial role in pain sensation and thermoregulation in humans. Gene mutations that cause loss of receptor function are associated with CONGENITAL INSENSITIVITY TO PAIN WITH ANHIDROSIS, while gene rearrangements that activate the protein-tyrosine kinase function are associated with tumorigenesis. 
Indexing Annotation English:   DF: RECEPT TRKA
History Note English:   2000; use RECEPTOR, TYPE 1 NEUROTROPHIC TYROSINE KINASE(NM) 1990-1999 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   34455 
Unique Identifier:   D020917 

Occurrence in VHL:
 

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